Physics of Biology

1902 Submissions

[32] viXra:1902.0502 [pdf] submitted on 2019-02-28 08:44:31

Mechanism Repairs DNA Damage

Authors: George Rajna
Comments: 75 Pages.

Researchers from the University of Copenhagen have identified a specific mechanism that protects cells from natural DNA errors that could permanently damage the genetic code and lead to diseases such as cancer. [41] DNA damage is occurring in our cells all the time due to external agents, such as exposure to sun, or internal agents, like reactive oxygen species. To detect and repair DNA lesions, cells have evolved DNA damage response. [40]
Category: Physics of Biology

[31] viXra:1902.0480 [pdf] submitted on 2019-02-27 10:39:57

Computer Network Disease Therapies

Authors: George Rajna
Comments: 71 Pages.

When Greg Bowman presents a slideshow about the proteins he studies, their 3-D shapes and folding patterns play out as animations on a big screen. [39] Researchers at the University of Helsinki uncovered the mechanisms for a novel cellular stress response arising from the toxicity of newly synthesized proteins. [38] Scientists have long sought to develop drug therapies that can more precisely diagnose, target and effectively treat life-threatening illness such as cancer, cardiovascular and autoimmune diseases. [37]
Category: Physics of Biology

[30] viXra:1902.0479 [pdf] submitted on 2019-02-27 10:58:06

Mechanism Behind DNA Damage

Authors: George Rajna
Comments: 73 Pages.

DNA damage is occurring in our cells all the time due to external agents, such as exposure to sun, or internal agents, like reactive oxygen species. To detect and repair DNA lesions, cells have evolved DNA damage response. [40] When Greg Bowman presents a slideshow about the proteins he studies, their 3-D shapes and folding patterns play out as animations on a big screen. [39] Researchers at the University of Helsinki uncovered the mechanisms for a novel cellular stress response arising from the toxicity of newly synthesized proteins. [38]
Category: Physics of Biology

[29] viXra:1902.0392 [pdf] submitted on 2019-02-24 01:39:48

Probing DNA Using UTM Related Concepts Based on HOL/Scala/JVM/Jikes RVM in the Context of Investigating Theoretical Aspects of Gene Therapy.

Authors: Nirmal Tej Kumar
Comments: 2 Pages. Short Communication & Technical Notes

Probing DNA Using UTM Related Concepts Based on HOL/Scala/JVM/Jikes RVM in the Context of Investigating Theoretical Aspects of Gene Therapy.
Category: Physics of Biology

[28] viXra:1902.0373 [pdf] submitted on 2019-02-23 04:58:58

Toxic Mitochondrial Proteins

Authors: George Rajna
Comments: 68 Pages.

Researchers at the University of Helsinki uncovered the mechanisms for a novel cellular stress response arising from the toxicity of newly synthesized proteins. [38] Scientists have long sought to develop drug therapies that can more precisely diagnose, target and effectively treat life-threatening illness such as cancer, cardiovascular and autoimmune diseases. [37] Skin cells taken from patients with a rare genetic disorder are up to ten times more sensitive to damage from ultraviolet A (AVA) radiation in laboratory tests, than those from a healthy population, according to new research from the University of Bath. [36]
Category: Physics of Biology

[27] viXra:1902.0367 [pdf] submitted on 2019-02-21 11:04:40

Regulating Neural Stem Cells

Authors: George Rajna
Comments: 64 Pages.

The use of stem cells to repair organs is one of the foremost goals of modern regenerative medicine. [35] Using new technology to reveal the 3-D organization of DNA in maturing male reproductive cells, scientists revealed a crucial period in development that helps explain how fathers pass on genetic information to future generations. [34] According to the Centers for Disease Control and Prevention, Down syndrome is the most common birth defect, occurring once in every 700 births. [33]
Category: Physics of Biology

[26] viXra:1902.0365 [pdf] submitted on 2019-02-21 11:42:57

Genetic Disease Protection

Authors: George Rajna
Comments: 66 Pages.

Skin cells taken from patients with a rare genetic disorder are up to ten times more sensitive to damage from ultraviolet A (AVA) radiation in laboratory tests, than those from a healthy population, according to new research from the University of Bath. [36] The use of stem cells to repair organs is one of the foremost goals of modern regenerative medicine. [35] Using new technology to reveal the 3-D organization of DNA in maturing male reproductive cells, scientists revealed a crucial period in development that helps explain how fathers pass on genetic information to future generations. [34]
Category: Physics of Biology

[25] viXra:1902.0356 [pdf] submitted on 2019-02-22 01:33:23

Disease-Sensing Nanomaterials

Authors: George Rajna
Comments: 67 Pages.

Scientists have long sought to develop drug therapies that can more precisely diagnose, target and effectively treat life-threatening illness such as cancer, cardiovascular and autoimmune diseases. [37] Skin cells taken from patients with a rare genetic disorder are up to ten times more sensitive to damage from ultraviolet A (AVA) radiation in laboratory tests, than those from a healthy population, according to new research from the University of Bath. [36] The use of stem cells to repair organs is one of the foremost goals of modern regenerative medicine. [35]
Category: Physics of Biology

[24] viXra:1902.0301 [pdf] submitted on 2019-02-18 12:58:54

3-D Arrangement of DNA

Authors: George Rajna
Comments: 62 Pages.

Using new technology to reveal the 3-D organization of DNA in maturing male reproductive cells, scientists revealed a crucial period in development that helps explain how fathers pass on genetic information to future generations. [34] According to the Centers for Disease Control and Prevention, Down syndrome is the most common birth defect, occurring once in every 700 births. [33] Healing is a complex process in adult skin impairments, requiring collaborative biochemical processes for onsite repair. [32]
Category: Physics of Biology

[23] viXra:1902.0289 [pdf] submitted on 2019-02-16 10:57:29

Platinum Treatment of Cancer Cells

Authors: George Rajna
Comments: 58 Pages.

Researchers at ETH Zurich recently demonstrated that platinum nanoparticles can be used to kill liver cancer cells with greater selectivity than existing cancer drugs. [31] “PPRIG was set up by NPL in 2012 to progress UK deployment of high-energy proton therapy,” explained Russell Thomas, senior research and clinical scientist at NPL and chair of PPRIG. [30] Researchers have moved closer to the real-time verification of hadron therapy, demonstrating the in vivo accuracy of simulations that predict particle range in the patient. [29]
Category: Physics of Biology

[22] viXra:1902.0280 [pdf] submitted on 2019-02-17 02:23:26

Skin Bioactive Glass-Gold Nanoparticles

Authors: George Rajna
Comments: 60 Pages.

Healing is a complex process in adult skin impairments, requiring collaborative biochemical processes for onsite repair. [32] Researchers at ETH Zurich recently demonstrated that platinum nanoparticles can be used to kill liver cancer cells with greater selectivity than existing cancer drugs. [31] “PPRIG was set up by NPL in 2012 to progress UK deployment of high-energy proton therapy,” explained Russell Thomas, senior research and clinical scientist at NPL and chair of PPRIG. [30]
Category: Physics of Biology

[21] viXra:1902.0278 [pdf] submitted on 2019-02-17 04:20:29

Down Syndrome DNA

Authors: George Rajna
Comments: 60 Pages.

According to the Centers for Disease Control and Prevention, Down syndrome is the most common birth defect, occurring once in every 700 births. [33] Healing is a complex process in adult skin impairments, requiring collaborative biochemical processes for onsite repair. [32] Researchers at ETH Zurich recently demonstrated that platinum nanoparticles can be used to kill liver cancer cells with greater selectivity than existing cancer drugs. [31]
Category: Physics of Biology

[20] viXra:1902.0260 [pdf] submitted on 2019-02-16 05:13:55

Upward Trajectory Proton Therapy

Authors: George Rajna
Comments: 57 Pages.

“PPRIG was set up by NPL in 2012 to progress UK deployment of high-energy proton therapy,” explained Russell Thomas, senior research and clinical scientist at NPL and chair of PPRIG. [30] Researchers have moved closer to the real-time verification of hadron therapy, demonstrating the in vivo accuracy of simulations that predict particle range in the patient. [29] A biomimetic nanosystem can deliver therapeutic proteins to selectively target cancerous tumors, according to a team of Penn State researchers. [28] Sunlight is essential for all life, and living organisms have evolved to sense and respond to light. [27]
Category: Physics of Biology

[19] viXra:1902.0228 [pdf] submitted on 2019-02-13 09:44:57

Magnetic Nanoparticles in Cells

Authors: George Rajna
Comments: 62 Pages.

Although magnetic nanoparticles are being used more and more in cell imaging and tissue bioengineering, what happens to them within stem cells in the long term remained undocumented. [42] Hyperbolic metamaterials are artificially made structures that can be formed by depositing alternating thin layers of a conductor such as silver or graphene onto a substrate. [41]
Category: Physics of Biology

[18] viXra:1902.0198 [pdf] submitted on 2019-02-11 07:32:31

Motor Enzyme Protects Genome

Authors: George Rajna
Comments: 48 Pages.

A helicase, Pfh1, can thanks to several different mechanisms protect the genome from DNA obstacles and damages associated with cancer. [28] The discovery that protein therapeutics can hijack the HOPS complex to gain access to the cell interior should help scientists design therapeutic proteins to treat diseases that are not adequately treated using other approaches, Schepartz said. [27] DNA regions susceptible to breakage and loss are genetic hot spots for important evolutionary changes, according to a Stanford study. [26]
Category: Physics of Biology

[17] viXra:1902.0179 [pdf] submitted on 2019-02-10 07:01:36

Biological Nanomaterials

Authors: George Rajna
Comments: 37 Pages.

Collaboration between material scientists, biologists and chemists could advance the development of self-assembling nanomaterials, called nanoarchitectonics, argues a review in the journal Science and Technology of Advanced Materials. [23] Brown University researchers have made a discovery about the way things stick together at tiny scales that could be helpful in engineering micro- and nanoscale devices. [22] University of Maryland researchers have created a fabric that can automatically regulate the amount of heat that passes through it. [21] At EPFL, Selman Sakar's research team has developed micromachines able to mechanically stimulate cells and microtissue. [20]
Category: Physics of Biology

[16] viXra:1902.0178 [pdf] submitted on 2019-02-10 08:27:33

Oxygen Tetrahedrons and Octahedrons in Biology

Authors: Zyryanova N.V., Savelyev I., Myakishev-Rempel M.
Comments: 7 Pages. In English и на русском языке

Uncentrosymmetric oxygen tetrahedrons and octahedrons produce piezoelectricity. In main biological molecules there are phosphorus-oxygen tetrahedrons. Biological molecules is uncentrosymmetric, and phosphorus-oxygen tetrahedrons enhance its reactivity. We suppose that oxygen octahedrons and tetrahedrons produce electricity in living organisms, and the electricity is condition for many biological phenomenon.
Category: Physics of Biology

[15] viXra:1902.0173 [pdf] submitted on 2019-02-10 03:35:11

Nanomachines Fight Cancer

Authors: George Rajna
Comments: 30 Pages.

Scientists from ITMO in collaboration with international colleagues have proposed new DNA-based nanomachines that can be used for gene therapy for cancer. [19] CRISPR is a technique that is revolutionizing biomedical research through high-precision genome editing. [18] The DNA molecules are chiral, which means they can exist in two forms which are mirror images, like a left and right hand. The phenomenon was dubbed "chiral induced spin selectivity" (CISS), and over the last few years, several experiments were published allegedly showing this CISS effect, even in electronic devices. [17]
Category: Physics of Biology

[14] viXra:1902.0172 [pdf] submitted on 2019-02-10 04:00:21

Gummy-Like Robots Prevent Disease

Authors: George Rajna
Comments: 31 Pages.

At EPFL, Selman Sakar's research team has developed micromachines able to mechanically stimulate cells and microtissue. [20] Scientists from ITMO in collaboration with international colleagues have proposed new DNA-based nanomachines that can be used for gene therapy for cancer. [19] CRISPR is a technique that is revolutionizing biomedical research through high-precision genome editing. [18] The DNA molecules are chiral, which means they can exist in two forms which are mirror images, like a left and right hand. The phenomenon was dubbed "chiral induced spin selectivity" (CISS), and over the last few years, several experiments were published allegedly showing this CISS effect, even in electronic devices. [17]
Category: Physics of Biology

[13] viXra:1902.0161 [pdf] submitted on 2019-02-08 22:48:09

Radio Frequency Water Treatment: Phenomenon and Explanation of Enhanced Water Transport in a Plant.

Authors: Andrew Holster
Comments: 38 Pages.

Radio frequency electromagnetic treatment of water using a commercial device (Vi Aqua Plantmate) was found to increase water transport in a plant by 20% - 35%, under suitable conditions. The experimental phenomenon is briefly presented, and the problem of explaining the effects is then examined. It is concluded that the EM treatment has long-lasting effects on water, and inferred that this reflects a structural property of the water. This water structure enhances capillarity and osmosis. It is suggested this is related to EZ structure. (Converted Powerpoint presentation from the 2017 Water Conference, Bulgaria).
Category: Physics of Biology

[12] viXra:1902.0145 [pdf] submitted on 2019-02-08 10:15:02

Protective Electromagnetic Fields

Authors: George Rajna
Comments: 63 Pages.

Scientists never suspected that they had any tangible impact on life on Earth. But a new Tel Aviv University study finds that these fields may have protective properties for organisms living under stress conditions. [42] A team led by University of Utah physicists has discovered how to fix a major problem that occurs in lasers made from a new type of material called quantum dots. [41] A team of researchers from the University of Central Florida and Michigan Technological University has developed a laser system concept built on the principles of supersymmetry. [40]
Category: Physics of Biology

[11] viXra:1902.0144 [pdf] submitted on 2019-02-08 10:39:53

Crispr Using Long DNA Fragments

Authors: George Rajna
Comments: 29 Pages.

CRISPR is a technique that is revolutionizing biomedical research through high-precision genome editing. [18] The DNA molecules are chiral, which means they can exist in two forms which are mirror images, like a left and right hand. The phenomenon was dubbed "chiral induced spin selectivity" (CISS), and over the last few years, several experiments were published allegedly showing this CISS effect, even in electronic devices. [17]
Category: Physics of Biology

[10] viXra:1902.0120 [pdf] submitted on 2019-02-06 14:28:31

A Mathematical Timeline of Our Universe

Authors: Arturo Tozzi
Comments: 13 Pages.

We propose an unusual history of the Universe, drawing a coherent chronology from pre-big bang scenarios to the occurence of the human brain. Our math-framed account emphasizes the explanatory role of broken symmetries and topological features in physical, biological, neuroscientific and medical events.
Category: Physics of Biology

[9] viXra:1902.0111 [pdf] submitted on 2019-02-07 04:52:18

DNA Molecular Mystery

Authors: George Rajna
Comments: 28 Pages.

The DNA molecules are chiral, which means they can exist in two forms which are mirror images, like a left and right hand. The phenomenon was dubbed "chiral induced spin selectivity" (CISS), and over the last few years, several experiments were published allegedly showing this CISS effect, even in electronic devices. [17] Chemist Ivan Huc finds the inspiration for his work in the molecular principles that underlie biological systems. [16] What makes particles self-assemble into complex biological structures? [15]
Category: Physics of Biology

[8] viXra:1902.0107 [pdf] submitted on 2019-02-06 07:39:14

Molecular DNA Repair

Authors: George Rajna
Comments: 38 Pages.

Using a piece of molecular "Velcro" to attach a light-emitting probe to a protein molecule, University of Wollongong (UOW) researchers have unlocked the mystery of how an important protein goes about repairing damaged DNA in bacteria, with implications for understanding how antibiotic resistance develops. [21] In new research, Hao Yan of Arizona State University and his colleagues describe an innovative DNA walker, capable of rapidly traversing a prepared track. [20] Just like any long polymer chain, DNA tends to form knots. Using technology that allows them to stretch DNA molecules and image the behavior of these knots, MIT researchers have discovered, for the first time, the factors that determine whether a knot moves along the strand or "jams" in place. [19]
Category: Physics of Biology

[7] viXra:1902.0100 [pdf] submitted on 2019-02-05 14:19:06

Longer Wavelength Optical Coherence Tomography

Authors: George Rajna
Comments: 29 Pages.

Optical coherence tomography (OCT) is a light-based imaging technique currently used in clinical diagnostics to examine organs in vivo. [17] This new approach illuminates the origin of surface electromagnetic waves and explains why these waves appear at interfaces where one of the medium parameters (dielectric permittivity or magnetic permeability) changes its sign. [16] A team of physicists headed by Professor Sebastian Reineke of TU Dresden has developed a new method of storing information in fully transparent plastic foils. [15] A new electron microscopy technique that detects the subtle changes in the weight of proteins at the nanoscale—while keeping the sample intact—could open a new pathway for deeper, more comprehensive studies of the basic building blocks of life. [14]
Category: Physics of Biology

[6] viXra:1902.0073 [pdf] submitted on 2019-02-04 05:16:47

Shining Light Kills Cancer Cells

Authors: George Rajna
Comments: 81 Pages.

A new compound based on Iridium, a rare metal which landed in the Gulf of Mexico 66 M years ago, hooked onto albumin, a protein in blood, can attack the nucleus of cancerous cells when switched on by light, University of Warwick researchers have found. [49] The wonder-material graphene could hold the key to unlocking the next generation of advanced, early stage lung cancer diagnosis. [48] Now, researchers from Brown University's School of Engineering have explained how the phenomenon works, and that explanation could pave the way for a new type of controlled molecular self-assembly. [47]
Category: Physics of Biology

[5] viXra:1902.0055 [pdf] submitted on 2019-02-04 04:56:30

Graphene Biosensor Cancer Diagnosis

Authors: George Rajna
Comments: 79 Pages.

The wonder-material graphene could hold the key to unlocking the next generation of advanced, early stage lung cancer diagnosis. [48] Now, researchers from Brown University's School of Engineering have explained how the phenomenon works, and that explanation could pave the way for a new type of controlled molecular self-assembly. [47] The team has turned graphene oxide (GO) into a soft, moldable and kneadable play dough that can be shaped and reshaped into free-standing, three-dimensional structures. [46] A team of researchers based at The University of Manchester have found a low cost method for producing graphene printed electronics, which significantly speeds up and reduces the cost of conductive graphene inks. [45]
Category: Physics of Biology

[4] viXra:1902.0047 [pdf] submitted on 2019-02-03 07:39:36

Tunneling Nanotubes of Cell

Authors: George Rajna
Comments: 24 Pages.

This work is an essential step toward understanding cell-to-cell communication via TNTs and lays the groundwork for investigations into their physiological functions and their role in the spread of pathogens, including viruses, bacteria and misfolded proteins. [15] A new electron microscopy technique that detects the subtle changes in the weight of proteins at the nanoscale—while keeping the sample intact—could open a new pathway for deeper, more comprehensive studies of the basic building blocks of life. [14] Researchers use a cavity-coupled double quantum dot to study electron-phonon interactions in a nanowire. [13]
Category: Physics of Biology

[3] viXra:1902.0021 [pdf] submitted on 2019-02-01 19:32:05

The Theory of Dove-Like Particles

Authors: Sun Zuodong
Comments: 38 Pages.

An enlightening viewpoint based on the theory of brain cell activation is to explore the pathogenesis and mechanism of sporadic Alzheimer's disease (AD) at molecular level by applying the principles of cell physics and biology. Its purpose is to coordinate and unify the existing theories of AD etiology and to solve the problems that have puzzled the research field of neurodegenerative diseases for a long time. Basic Contents: Excessive cations are transferred from extracellular to intracellular, and compete with potassium ions on the inner surface of the cell membrane. As a result, the action potential produced can not activate calcium channels normally, leading to abnormal apoptosis of brain cells. Amyloid plaques are the remains of abnormal apoptotic brain cells. Amyloid plaques are aggregated by van der Waals force and electrostatic attraction between amyloid plaques. The interstitium is amyloid protein. Brain cells consist of neurons, microglia and astrocytes in turn. Most of the spotted nuclei in the remains are cations. Applicable but not limited to neurodegenerative diseases such as Alzheimer's disease, physical means should be preferred to solve such diseases.
Category: Physics of Biology

[2] viXra:1902.0013 [pdf] submitted on 2019-02-01 07:15:46

Liquid Superlenses Biophotonics

Authors: George Rajna
Comments: 98 Pages.

In a new method, materials scientists Boliang Jia and colleagues at the departments of mechanical engineering and robotics presented a printable biocompatible superlens placed directly on objects of interest to observe subdiffraction-limited features (resolution beyond the diffraction limit). [54] Physicists have also devised photonic topological insulators, synthetic materials that impart light waves with distinct topological features, allowing light (rather than electric currents) to flow via topological surface states. [53] "This research highlights the cutting-edge research being done at WVU, and we are very excited to see their work appear in the very high-profile journal Nature Communications." [52]
Category: Physics of Biology

[1] viXra:1902.0011 [pdf] submitted on 2019-02-01 08:01:44

Dynamic Aspirin Molecular Vibrations

Authors: George Rajna
Comments: 99 Pages.

Aspirin is not only an important drug, but also an interesting physics model system in which molecular vibrations and electrons are coupled in a particular way. [55] In a new method, materials scientists Boliang Jia and colleagues at the departments of mechanical engineering and robotics presented a printable biocompatible superlens placed directly on objects of interest to observe subdiffraction-limited features (resolution beyond the diffraction limit). [54] Physicists have also devised photonic topological insulators, synthetic materials that impart light waves with distinct topological features, allowing light (rather than electric currents) to flow via topological surface states. [53]
Category: Physics of Biology