This essay explores the fundamental contradiction between the biological evolutionary mechanisms that forged human intelligence and the ethical foundations of modern civilization. The author posits that human intellect has exceeded the immediate demands of biological survival, creating a rift between biological modification and civilizational progress. Under current Holocene conditions, natural selection no longer rewards high cognitive traits, threatening a gradual, unnoticed cognitive decline—a trajectory historically illustrated by Homo floresiensis. Furthermore, the engineering limitations of the biological body, particularly its vulnerability to cosmic radiation, impose a definitive ceiling on space expansion, offering a novel resolution to the Fermi Paradox. The essay argues that the long-term preservation of intelligence requires a deliberate transition to non-biological substrates capable of serving as carriers of the mind—substrates for which artificial intelligence and neural interfaces can be seen as the first precursors. This shift represents a new stage of existential responsibility and the sole pathway to liberate intellect from biological constraints, allowing the future evolution of the mind to transcend current human comprehension.