Authors: George Rajna
The ability to precisely transport and position individual cells and microscopic particles in fluids could provide a powerful tool for a wide range of biomedical applications, including targeted drug delivery, nanomedicine and tissue engineering.  Developing an efficient delivery system for enhanced and controlled gene interference-based therapeutics is an existing challenge in molecular biology.  This fact makes lensless microscopy an ideal tool for medical diagnosis in remote areas since there is no need for the medical doctor to bring and maintain large, heavy and sensitive analysis devices.  The Columbia team behind the revolutionary 3-D SCAPE microscope announces today a new version of this high-speed imaging technology.  The discovery that protein therapeutics can hijack the HOPS complex to gain access to the cell interior should help scientists design therapeutic proteins to treat diseases that are not adequately treated using other approaches, Schepartz said.  DNA regions susceptible to breakage and loss are genetic hot spots for important evolutionary changes, according to a Stanford study.  For the English scientists involved, perhaps the most important fact is that their DNA read was about twice as long as the previous record, held by their Australian rivals.  Researchers from the University of Chicago have developed a high-throughput RNA sequencing strategy to study the activity of the gut microbiome.  Today a large international consortium of researchers published a complex but important HYPERLINK "https://www.nature.com/articles/s41586-018-0734-6" study looking at how DNA works in animals.  Asymmetry plays a major role in biology at every scale: think of DNA spirals, the fact that the human heart is positioned on the left, our preference to use our left or right hand ... 
Comments: 57 Pages.
[v1] 2019-10-29 05:07:07
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