Predation can drive significant effect upon the community structure. However, the observation and documentation of this ecological interaction is occasional and yet scarce for many groups. Our goal here is to report the predation of Dermatonotus muelleri (Boettger, 1885) by Guira guira (Gmelin, JF, 1788). Because G. guira diet frequently includes small vertebrates we believe that this species may act as an important regulator of D. muelleri population. This predation report can input insights about the knowledge of interactions of Microhylidae Günther, 1858 (1843) members and others species.
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