Physics of Biology

   

Bacteria Produce New Molecules

Authors: George Rajna

By enticing away the repressors dampening unexpressed, silent genes in Streptomyces bacteria, researchers at the University of Illinois have unlocked several large gene clusters for new natural products, according to a study published in the journal Nature Chemical Biology. [28] Imagine trying to figure out how something works when that something takes place in a space smaller than a femtoliter: one quadrillionith of a liter. [27] A new NYU Abu Dhabi study suggests for the first time that actin, which is a cytoskeleton protein found in the cell, is critical to regulating the genome-the genetic material of an organism-during the formation of "neurons" or nerve cells. [26] For the English scientists involved, perhaps the most important fact is that their DNA read was about twice as long as the previous record, held by their Australian rivals. [25] Researchers from the University of Chicago have developed a high-throughput RNA sequencing strategy to study the activity of the gut microbiome. [24] Today a large international consortium of researchers published a complex but important study looking at how DNA works in animals. [23] Asymmetry plays a major role in biology at every scale: think of DNA spirals, the fact that the human heart is positioned on the left, our preference to use our left or right hand ... [22] Scientists reveal how a 'molecular machine' in bacterial cells prevents fatal DNA twisting, which could be crucial in the development of new antibiotic treatments. [21] In new research, Hao Yan of Arizona State University and his colleagues describe an innovative DNA HYPERLINK "https://phys.org/tags/walker/" walker, capable of rapidly traversing a prepared track. [20] Just like any long polymer chain, DNA tends to form knots. Using technology that allows them to stretch DNA molecules and image the behavior of these knots, MIT researchers have discovered, for the first time, the factors that determine whether a knot moves along the strand or "jams" in place. [19]

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[v1] 2019-01-01 11:53:46

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