Structure of Acetaminophen Alias Paracetemol or Tylenol at the Atomic Level

Authors: Raji Heyrovska

The recent new rapid technique of determining structures of molecules by CryoEM Method microED techniques by Gonen et al, aroused the interest to compare the reported bond lengths for acetaminophen with the additivity of adajacent atomic radii rule. The latter was found by the author to explain the bond lengths in many small as well as large molecules. The bond distances obtained by conventional methods and those found by Grunen et al by electron diffraction agree well with the additivity rule, whereas those by the Gonen group seem slightly smaller. A possible reason is discussed here.

Comments: Pages. 5 Figures, Table 1. In the acknowledgement, Tim Gonen should read Tamir Gonen.

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[v1] 2018-11-16 13:28:29

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