Authors: Ilija Barukčić
Objective: Many times a positive relationship between Helicobacter pylori infection and gastric cancer has been reported, yet findings are inconsistent. Methods: A literature search in PubMed was performed to re-evaluate the relationship between Helicobacter pylori (HP) and carcinoma of human stomach. Case control studies with a least 500 participants were consider for a review and meta-analysis. The meta-/re-analysis was conducted using conditio-sine qua non relationship and the causal relationship k. Significance was indicated by a p-value of less than 0.05. Result: All studies analyzed provide impressive evidence of a cause effect relationship between H. pylori and gastric cancer (GC). Two very great studies were able to make the proof that H. pylori is a necessary condition of human gastric cancer. In other words, without H. pylori infection no human gastric cancer. Conclusion: Our findings indicate that Helicobacter pylori (H. pylori) is the cause of gastric carcinoma.
Comments: 50 pages. Copyright © 2017 by Ilija Barukčić, Horandstrasse, Jever, Germany. Published by:
[v1] 2017-12-03 02:40:26
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