Authors: Ilija Barukčić
Objective: A series of different studies detected Human papillomavirus (HPV) in malignant and nonmalignant prostate tissues. However, the results of studies on the relationship between HPV infections and prostate cancer (PCa) remain controversial. Methods: A systematic review and re-analysis of some polymerase-chain reaction (PCR) based case-control studies was performed aimed to answer the following question: Is there a cause effect relationship between human papillomavirus (HPV) and prostatic cancer? The method of the conditio per quam relationship was used to proof the hypothesis: if presence of human papillomavirus (HPV) in human prostate tissues then presence of prostate carcinoma. The mathematical formula of the causal relationship k was used to proof the hypothesis, whether there is a cause effect relationship between human papillomavirus (HPV) and prostate cancer. Significance was indicated by a p-value of less than 0.05. Result: Only one of the studies analyzed failed to provide evidence that there is a cause-effect relationship between human papillomavirus (HPV) and prostate cancer. Two studies were highly significant on this point. The majority of the studies analyzed support the hypothesis that human papillomavirus (HPV) is a sufficient condition of prostate cancer. In other words, if presence of human papillomavirus (HPV) in human prostate tissues then presence of prostate cancer. Conclusion: Human papillomavirus (HPV) is a cause of prostate cancer.
Comments: 57 pages. Copyright © 2017 by Ilija Barukčić, Horandstrasse, Jever, Germany. Published by:
[v1] 2017-11-26 08:58:37
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