It is known that patients with pulmonary hypertension show an augmented ventilatory response to exercise defined as the slope of minute ventilation over carbon dioxide production (VE/VCO2). We suggested that the degree of ventilatory augmentation may be used to differentiate between patients with primary pulmonary hypertension (PPH), Eisenmenger (E.) and chronic thromboembolic (CH.TH.EM.) disease.
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