Authors: Ilija Barukčić
Comments: 26 pages. Copyright © 2018 by Ilija Barukčić, Jever, Germany. Published by:.
BACKGROUND: Cytomegalovirus (CMV) infection has been supposed to play an important role in the pathogenesis of atherosclerosis (AS). Although many authors proved the presence of viral DNA in arterial wall tissue, the role of CMV in the origin and progress of athero-sclerosis still remains unclear and no definite consensus has been reached. Whether CMV may be involved in the development of AS has not yet been established. METHODS: The purpose of this study was to investigate whether CMV and AS are causally related. Literature was searched through the electronic database PubMed. Data were accurately assessed and analyzed. RESULTS: The meta-analysis results showed that CMV infection and AS are causally connected. CONCLUSIONS: Cytomegalovirus is the cause of atherosclerosis. Keywords Cytomegalovirus, atherosclerosis, causal relationship