Physics of Biology

1910 Submissions

[24] viXra:1910.0253 [pdf] submitted on 2019-10-15 04:53:14

Tackle Radioresistant Melanoma

Authors: George Rajna
Comments: 61 Pages.

Microbeam radiation therapy (MRT) uses synchrotron X-ray beams to deliver spatially fractionated radiation, with extremely high peak doses deposited in the microbeam path and tissue located between the microbeams receiving only a small fraction of this dose. [38] The new technology can successfully measure heart rate and oxygen saturation. It also has the potential to measure blood pressure and cardiac output, whilst maintaining its flexible and transparent form. [37] Electrical engineers at Duke University have devised a fully print-in-place technique for electronics that is gentle enough to work on delicate surfaces including paper and human skin. [36]
Category: Physics of Biology

[23] viXra:1910.0252 [pdf] submitted on 2019-10-15 05:11:37

Alphabet of Origami

Authors: George Rajna
Comments: 76 Pages.

This discovery could help in the construction of origami robots and toward designing smart programmable materials. [51] A team of researchers from the Chinese Academy of Sciences, Vanderbilt University and the University of Maryland has created origami-like structures made out of graphene using scanning tunneling microscopy. In their paper published in the journal Science, the group explains how they achieved this feat and possible applications. [50] Platinum has long been used as a catalyst to enable the oxidation reduction reaction at the center of fuel cell technology. [49] Titanium oxide (TiO2) nanofibers can have various applications, such as in catalyzers and filters. [48] Today, scientists report progress in making versions of these nanoparticles that could someday give built-in night vision to humans. [47] A new piece of a difficult puzzle-the nature of memory-fell into place this week with a hint at how brain cells change structure when they learn something. [46] Researchers at the University of Alberta have found an important protein in the cells of a deadly infectious parasite, opening the door to less harmful treatment for millions of people suffering from diseases like sleeping sickness in Africa and Chagas disease in South America. [45] The remarkable ability of a small Australian sea snail to produce a colourful purple compound to protect its eggs is proving even more remarkable for its potential in a new anti-cancer pharmaceutical. [44] Gene editing technology is a technology that eliminates the underlying causes of and treats diseases by removing specific genesor editing genes to restore their normal function. In particular, CRISPR gene editing technology is now commonly used for immunotherapy by correcting the genes of immune cells to induce them to attack cancer cells selectively. [43]
Category: Physics of Biology

[22] viXra:1910.0226 [pdf] submitted on 2019-10-14 08:48:59

Protein-Folded DNA Nanostructures

Authors: George Rajna
Comments: 41 Pages.

By using proteins that naturally bind and arrange DNA inside cells, a KAUST-led team has devised a plug-and-play strategy for building stable, custom-designed nanostructures. [25] Scientists at the Max Planck Institute for Plant Breeding Research in Cologne have now discovered how a protein called LMI1 can control leaf growth and shape. [24] One way we might actually prove our biological complexity is to look at the number of different proteins that our bodies can produce for building all our different types of cells and the other things they need. [23]
Category: Physics of Biology

[21] viXra:1910.0215 [pdf] submitted on 2019-10-13 03:56:58

Iron in Soils Immobilize Arsenic

Authors: George Rajna
Comments: 52 Pages.

Sandia National Laboratories researchers have discovered the mechanism to "switch on" iron residing in clay mineral structures, leading to the understanding of how to make iron reactive under oxygen-free conditions. [31] One such process has now been elucidated by a team led by Prof. Matthias Kling and Dr. Boris Bergues at the Laboratory for Attosecond Physics (LAP), which is jointly run by Ludwig-Maximilians Universität (LMU) and the Max Planck Institute of Quantum Optics (MPQ). [30] Photoacoustic computed tomography (PACT) is a non-invasive hybrid imaging technique that excites biological tissues with light and detects the subsequently generated ultrasound to form images. [29]
Category: Physics of Biology

[20] viXra:1910.0206 [pdf] submitted on 2019-10-13 07:36:28

Transparent Graphene Wearables Monitor

Authors: George Rajna
Comments: 57 Pages.

The new technology can successfully measure heart rate and oxygen saturation. It also has the potential to measure blood pressure and cardiac output, whilst maintaining its flexible and transparent form. [37] Electrical engineers at Duke University have devised a fully print-in-place technique for electronics that is gentle enough to work on delicate surfaces including paper and human skin. [36] Called the Quantum Material Press, or QPress, this system will accelerate the discovery of next-generation materials for the emerging field of quantum information science (QIS). [35]
Category: Physics of Biology

[19] viXra:1910.0190 [pdf] submitted on 2019-10-12 04:10:53

DNA Fighting Back Virus

Authors: George Rajna
Comments: 38 Pages.

A virus that infects koalas is steadily integrating itself into their DNA, ensuring that it is passed down from generation to generation. But the koala genome is defending itself, revealing that DNA has its own immune system to shut down invaders. [22] Scientists reveal how a 'molecular machine' in bacterial cells prevents fatal DNA twisting, which could be crucial in the development of new antibiotic treatments. [21] In new research, Hao Yan of Arizona State University and his colleagues describe an innovative DNA walker, capable of rapidly traversing a prepared track. [20] Just like any long polymer chain, DNA tends to form knots. Using technology that allows them to stretch DNA molecules and image the behavior of these knots, MIT researchers have discovered, for the first time, the factors that determine whether a knot moves along the strand or "jams" in place. [19] Researchers at Delft University of Technology, in collaboration with colleagues at the Autonomous University of Madrid, have created an artificial DNA blueprint for the replication of DNA in a cell-like structure. [18] An LMU team now reveals the inner workings of a molecular motor made of proteins which packs and unpacks DNA. [17] Chemist Ivan Huc finds the inspiration for his work in the molecular principles that underlie biological systems. [16] What makes particles self-assemble into complex biological structures? [15] Scientists from Moscow State University (MSU) working with an international team of researchers have identified the structure of one of the key regions of telomerase-a so-called "cellular immortality" ribonucleoprotein. [14] Researchers from Tokyo Metropolitan University used a light-sensitive iridium-palladium catalyst to make "sequential" polymers, using visible light to change how building blocks are combined into polymer chains. [13] Researchers have fused living and non-living cells for the first time in a way that allows them to work together, paving the way for new applications. [12]
Category: Physics of Biology

[18] viXra:1910.0187 [pdf] submitted on 2019-10-12 06:00:20

Chiral Asymmetry of D. Hofstadter’s Typogenetics

Authors: Perry W Swanborough
Comments: 12 Pages.

Typographical genetics (“Typogenetics”) introduced by Douglas Hofstadter in 1979 is an abstract recursive logic system which has been studied subsequently for insights into self-reproduction. There are immediately-observable asymmetries in the early formulations of Typogenetics, but after design of a triplet-codon Typogenetics to eliminate these, fundamental irreducible asymmetry remains. It is noted that both Typogenetics and self-reproduction of cellular automaton loop structures share the property of chiral asymmetry.
Category: Physics of Biology

[17] viXra:1910.0186 [pdf] submitted on 2019-10-12 06:06:35

Opencell: a Hypothetical Cure for a Genetic Disease, or Cancer, Using a Simulation Like Openworm

Authors: Domenico Oricchio
Comments: 1 Page.

A simulation of a cure on a complete mathematical model of a human cell may be possible, to accelerate pharmacological research
Category: Physics of Biology

[16] viXra:1910.0178 [pdf] submitted on 2019-10-11 03:14:15

Biomimetic Energy Transport

Authors: George Rajna
Comments: 61 Pages.

Scientists from the University of Groningen (the Netherlands) and the University of Würzburg (Germany) have investigated a simple biomimetic light-harvesting system using advanced spectroscopy combined with a microfluidic platform. [42] Gallium nitride, a semiconductor that revolutionized energy-efficient LED lighting, could also transform electronics and wireless communication, thanks to a discovery made by Cornell researchers. [41] The signals from a lighthouse to ships at sea is an early example of optical communication, the use of light to transmit information. [40]
Category: Physics of Biology

[15] viXra:1910.0175 [pdf] submitted on 2019-10-11 04:51:41

Nanostructures Reduce Adhesion of Bacteria

Authors: George Rajna
Comments: 68 Pages.

Now a team of researchers has discovered that precise analysis of the topographical composition of nanostructured surfaces provides a direct means of deriving the adhesive forces that bind bacteria to a surface. [38] The group of NanoBiotechnology at IMDEA Nanociencia, led by Prof. Álvaro Somoza, has used gold nanoclusters coated with albumin to facilitate the attachment of two active molecules for the treatment of breast cancer. [37] Microtubules are protein polymers that assemble into dynamic structures, essential for cell division, shape, motility, and transport of intracellular cargos. [36]
Category: Physics of Biology

[14] viXra:1910.0160 [pdf] submitted on 2019-10-10 04:24:56

Nanoparticles Impact on Environment

Authors: George Rajna
Comments: 62 Pages.

This discovery at the chemistry-biology interface is a first step toward developing new sustainable materials and practices, as well as providing the groundwork for possible remediation approaches." [38] Researchers at University of Utah Health developed a proof-of-concept technology using nanoparticles that could offer a new approach for oral medications. [37] Using scanning tunneling microscopy (STM), extremely high resolution imaging of the molecule-covered surface structures of silver nanoparticles is possible, even down to the recognition of individual parts of the molecules protecting the surface. [36] A fiber optic sensing system developed by researchers in China and Canada can peer inside supercapacitors and batteries to observe their state of charge. [35] The idea of using a sound wave in optical fibers initially came from the team's partner researchers at Bar-Ilan University in Israel. Joint research projects should follow. [34] Researchers at the Technion-Israel Institute of Technology have constructed a first-of-its-kind optic isolator based on resonance of light waves on a rapidly rotating glass sphere. [33] The micro-resonator is a two-mirror trap for the light, with the mirrors facing each other within several hundred nanometers. [32] "The realization of such all-optical single-photon devices will be a large step towards deterministic multi-mode entanglement generation as well as high-fidelity photonic quantum gates that are crucial for all-optical quantum information processing," says Tanji-Suzuki. [31] Researchers at ETH have now used attosecond laser pulses to measure the time evolution of this effect in molecules. [30] A new benchmark quantum chemical calculation of C2, Si2, and their hydrides reveals a qualitative difference in the topologies of core electron orbitals of organic molecules and their silicon analogues. [29]
Category: Physics of Biology

[13] viXra:1910.0136 [pdf] submitted on 2019-10-09 10:18:20

DNA-PAINT Microscopy at Speed

Authors: George Rajna
Comments: 31 Pages.

Recent advances in fluorescence microscopy allow researchers to study biological processes below the classical diffraction limit of light. [20] Scientists at the U.S. Department of Energy's Ames Laboratory are now able to see greater details of DNA origami nanostructures, which will lead to a greater understanding and control of their assembly for future applications. [19] Nanocages are highly interesting molecular constructs, from the point of view of both fundamental science and possible applications. [18]
Category: Physics of Biology

[12] viXra:1910.0111 [pdf] submitted on 2019-10-08 08:12:24

Precancerous Detection with Nanodiamonds

Authors: George Rajna
Comments: 38 Pages.

Scientists at the National Research Nuclear University MEPhI (MEPhI) have studied the optical properties of detonation nanodiamonds when interacting with various biomacromolecules (biopolymer molecules). [24] The Pt nanoreactor was designed with a controlled core-shell structure and morphology for the visual detection of metabolic biomarkers and direct laser desorption/ionization MS fingerprinting of the native serum. [23]
Category: Physics of Biology

[11] viXra:1910.0069 [pdf] submitted on 2019-10-06 06:24:20

Printed Electronics for Biosensors

Authors: George Rajna
Comments: 55 Pages.

Electrical engineers at Duke University have devised a fully print-in-place technique for electronics that is gentle enough to work on delicate surfaces including paper and human skin. [36] Called the Quantum Material Press, or QPress, this system will accelerate the discovery of next-generation materials for the emerging field of quantum information science (QIS). [35] A novel technique that nudges single atoms to switch places within an atomically thin material could bring scientists another step closer to realizing theoretical physicist Richard Feynman's vision of building tiny machines from the atom up. [34]
Category: Physics of Biology

[10] viXra:1910.0067 [pdf] submitted on 2019-10-06 06:47:35

View Inside a Living Mouse's Brain

Authors: George Rajna
Comments: 56 Pages.

The researchers said their technique could also enable surgeons to more precisely excise tumors and aid biologists and medical researchers in studying fundamental processes within cells. [37] Electrical engineers at Duke University have devised a fully print-in-place technique for electronics that is gentle enough to work on delicate surfaces including paper and human skin. [36] Called the Quantum Material Press, or QPress, this system will accelerate the discovery of next-generation materials for the emerging field of quantum information science (QIS). [35] A novel technique that nudges single atoms to switch places within an atomically thin material could bring scientists another step closer to realizing theoretical physicist Richard Feynman's vision of building tiny machines from the atom up. [34]
Category: Physics of Biology

[9] viXra:1910.0059 [pdf] submitted on 2019-10-05 05:11:35

CRISPR Alter the Microbiome

Authors: George Rajna
Comments: 43 Pages.

Researchers at Western University have developed a new way to deliver the DNA-editing tool CRISPR-Cas9 into microorganisms in the lab, providing a way to efficiently launch a targeted attack on specific bacteria. [26] The work reflects a growing trend at both the Salk Institute and elsewhere toward integrating computational approaches into biology research. [25] That's only a smattering of what scientists will be able to examine with the new microscope—an atomic force-Raman microscope, to be exact—now housed in the University of Delaware's Lammot du Pont Laboratory. [24] The Pt nanoreactor was designed with a controlled core-shell structure and morphology for the visual detection of metabolic biomarkers and direct laser desorption/ionization MS fingerprinting of the native serum. [23]
Category: Physics of Biology

[8] viXra:1910.0058 [pdf] submitted on 2019-10-05 05:13:37

Protein Networks Behind Tumor Growth

Authors: George Rajna
Comments: 31 Pages.

Researchers at the University of Copenhagen have used highly sophisticated molecular analyses to identify key proteins in the signaling pathways that cancers use to spread in the body. The study could help in personalizing cancer treatment and developing new drugs. [20] To fully understand how genome integrity is maintained, David Cortez, Ph.D., and colleagues have generated a "catalog" of the proteins present at sites of DNA duplication (replication forks) and chromatin packaging of newly synthesized DNA. [19] Researchers at Delft University of Technology, in collaboration with colleagues at the Autonomous University of Madrid, have created an artificial DNA blueprint for the replication of DNA in a cell-like structure. [18]
Category: Physics of Biology

[7] viXra:1910.0057 [pdf] submitted on 2019-10-05 05:15:32

Cutting-Edge Microscopy

Authors: George Rajna
Comments: 42 Pages.

The work reflects a growing trend at both the Salk Institute and elsewhere toward integrating computational approaches into biology research. [25] That's only a smattering of what scientists will be able to examine with the new microscope—an atomic force-Raman microscope, to be exact—now housed in the University of Delaware's Lammot du Pont Laboratory. [24] The Pt nanoreactor was designed with a controlled core-shell structure and morphology for the visual detection of metabolic biomarkers and direct laser desorption/ionization MS fingerprinting of the native serum. [23]
Category: Physics of Biology

[6] viXra:1910.0056 [pdf] submitted on 2019-10-05 05:17:46

NMR Approach for Cell Content

Authors: George Rajna
Comments: 31 Pages.

Researchers in Utrecht have found a new way to observe membraneless compartments at an unprecedented level of resolution. [20] To fully understand how genome integrity is maintained, David Cortez, Ph.D., and colleagues have generated a "catalog" of the proteins present at sites of DNA duplication (replication forks) and chromatin packaging of newly synthesized DNA. [19] Researchers at Delft University of Technology, in collaboration with colleagues at the Autonomous University of Madrid, have created an artificial DNA blueprint for the replication of DNA in a cell-like structure. [18]
Category: Physics of Biology

[5] viXra:1910.0055 [pdf] submitted on 2019-10-05 05:19:33

DNA Replication Catalog

Authors: George Rajna
Comments: 29 Pages.

To fully understand how genome integrity is maintained, David Cortez, Ph.D., and colleagues have generated a "catalog" of the proteins present at sites of DNA duplication (replication forks) and chromatin packaging of newly synthesized DNA. [19] Researchers at Delft University of Technology, in collaboration with colleagues at the Autonomous University of Madrid, have created an artificial DNA blueprint for the replication of DNA in a cell-like structure. [18] An LMU team now reveals the inner workings of a molecular motor made of proteins which packs and unpacks DNA. [17] Chemist Ivan Huc finds the inspiration for his work in the molecular principles that underlie biological systems. [16]
Category: Physics of Biology

[4] viXra:1910.0049 [pdf] submitted on 2019-10-05 05:43:41

Microscope with Dual Capabilities

Authors: George Rajna
Comments: 40 Pages.

That's only a smattering of what scientists will be able to examine with the new microscope—an atomic force-Raman microscope, to be exact—now housed in the University of Delaware's Lammot du Pont Laboratory. [24] The Pt nanoreactor was designed with a controlled core-shell structure and morphology for the visual detection of metabolic biomarkers and direct laser desorption/ionization MS fingerprinting of the native serum. [23] Nuclear technology companies Phoenix and SHINE Medical Technologies have achieved a new world record for a nuclear fusion reaction in a steady-state system, the strongest of its kind ever produced on Earth. [22]
Category: Physics of Biology

[3] viXra:1910.0048 [pdf] submitted on 2019-10-05 05:45:42

Cancer Diagnosis with Platinum Nanoreactor

Authors: George Rajna
Comments: 37 Pages.

The Pt nanoreactor was designed with a controlled core-shell structure and morphology for the visual detection of metabolic biomarkers and direct laser desorption/ionization MS fingerprinting of the native serum. [23] Nuclear technology companies Phoenix and SHINE Medical Technologies have achieved a new world record for a nuclear fusion reaction in a steady-state system, the strongest of its kind ever produced on Earth. [22] Bacterial systems are some of the simplest and most effective platforms for the expression of recombinant proteins. [21]
Category: Physics of Biology

[2] viXra:1910.0047 [pdf] submitted on 2019-10-05 05:47:54

Medical Isotope Production

Authors: George Rajna
Comments: 36 Pages.

Nuclear technology companies Phoenix and SHINE Medical Technologies have achieved a new world record for a nuclear fusion reaction in a steady-state system, the strongest of its kind ever produced on Earth. [22] Bacterial systems are some of the simplest and most effective platforms for the expression of recombinant proteins. [21] Now, in a new paper published in Nature Structural & Molecular Biology, Mayo researchers have determined how one DNA repair protein gets to the site of DNA damage. [20]
Category: Physics of Biology

[1] viXra:1910.0040 [pdf] submitted on 2019-10-05 06:02:37

Quantizing DNA Metamolecules

Authors: George Rajna
Comments: 40 Pages.

Tailored metal nanoclusters can be actively developed in the lab to manipulate light at the subwavelength scale for nanophotonic applications. [21] Researchers at the University of Wollongong's (UOW) Molecular Horizons initiative have shed new light on how an important but not well understood protein goes about its vital role of reducing errors and mutations in DNA replication. [20] DNA is a lengthy molecule—approximately 1,000-fold longer than the cell in which it resides—so it can't be jammed in haphazardly. [19]
Category: Physics of Biology