Paracetamol and piroxicam are non-steroidal anti-inflammatory drugs (NSAIDs), widely used in pain and inflammatory diseases. The present study aimed to evaluate the impact of biofield treatment on spectral properties of paracetamol and piroxicam. The study was performed in two groups (control and treatment) of each drug. The control groups remained as untreated, and biofield treatment was given to treatment groups. Subsequently, spectral properties of both drugs before and after biofield treatment were characterized using FT-IR and UV-Vis spectroscopic techniques. FT-IR data of paracetamol showed N-H amide II bending peak in biofield treated paracetamol, which was shifted to lower wavenumber (1565 to 1555 cm-1) as compared to control. Further, the intensity of vibrational peaks in the range of 1171-965 cm-1 (C-O and C-N stretching) were increased in treated sample of paracetamol as compared to control. Similarly, the FT-IR data of piroxicam (treated) showed increased intensity of vibrational peaks at 1628 (amide C=O stretching), 1576-1560 cm-1 (C=C stretching) with respect to control peaks. Furthermore, vibrational peak of C=N stretching (1467 cm-1) was observed in biofield treated piroxicam. This peak was not observed in control sample, possibly due to its low intensity. Based on FT-IR data, it is speculated that bond length and dipole moment of some bonds like N-H (amide), C-O, and C-N in paracetamol and C=O (amide), C=N, and C=C in piroxicam might be changed due to biofield treatment. The UV spectrum of biofield treated paracetamol showed the shifting in wavelength of UV absorption as 243→248.2 nm and 200→203.4 nm as compared to control. Likely, the lambda max (λmax) of treated piroxicam was also shifted as 328 →345.6 nm, 241→252.2 nm, and 205.2→203.2 nm as compared to control. Overall results showed an impact of biofield treatment on the spectral properties of paracetamol and piroxicam.
The stability of any pharmaceutical compound is most desired quality that determines its shelf life and effectiveness. The stability can be correlated to structural and bonding properties of compound and any variation arise in these properties can be easily determined by spectroscopic analysis. The present study was aimed to evaluate the impact of biofield treatment on these properties of four pharmaceutical compounds such as urea, thiourea, sodium carbonate, and magnesium sulphate, using spectroscopic analysis. Each compound was divided into two groups, referred as control and treatment. The control groups remained as untreated and treatment group of each compound received Mr. Trivedi’s biofield treatment. Control and treated samples of each compound were characterized using FourierTransform Infrared (FT-IR) and Ultraviolet-Visible (UV-Vis) spectroscopy. FT-IR spectra of biofield treated urea showed the shifting of C=O stretching peak towards lower frequency (1684→1669 cm-1) and N-H stretching peak towards higher frequency (3428→3435 cm-1) with respect to control. A shift in frequency of C-N-H bending peak was also observed in treated sample as compared to control i.e. (1624→1647 cm-1). FT-IR spectra of thiourea showed upstream shifting of NH2 stretching peak (3363→3387 cm-1) as compared to control, which may be due to decrease in N-H bond length. Also, the change in frequency of N-C-S bending peak (621→660 cm-1) was observed in treated thiourea that could be due to some changes in bond angle after biofield treatment. Similarly, treated sample of sodium carbonate showed decrease in frequency of C-O bending peak (701→690 cm-1) and magnesium sulphate showed increase in frequency of S-O bending peak (621→647 cm-1) as compared to control, which indicated that bond angle might be altered after biofield treatment on respective samples. UV-Vis spectra of biofield treated urea showed shift in lambda max (λmax) towards higher wavelength (201→220 nm) as compared to control sample, whereas other compounds i.e. thiourea, sodium carbonate, and magnesium sulphate showed the similar λmax to their respective control. These findings conclude that biofield treatment has significant impact on spectral properties of tested pharmaceutical compounds which might be due to some changes happening at atomic level of compounds, and leading to affect the bonding and structural properties of compounds.
In Mn3 O4 , the crystal structure, dislocation density, particle size and spin of the electrons plays crucial role in modulating its magnetic properties. Present study investigates impact of Biofield treatment on physical and atomic properties of Mn3 O4 . X-ray diffraction revealed the significant effect of biofield on lattice parameter, unit cell volume, molecular weight, crystallite sizes and densities of treated Mn3 O4 . XRD analysis confirmed that crystallinity was enhanced and dislocation density was effectively reduced by 80%. FTIR spectroscopic analysis revealed that Mn-O bond strength was significantly altered by biofield treatment. Electronic spin resonance analysis showed higher g-factor of electron in treated Mn3 O4 as compared to control, along with altered spin-spin atomic interaction of Mn with other mixed valance states. Additionally, ESR study affirmed higher magnetization behaviour of the treated Mn3 O4 . The results demonstrated that treated Mn3O4 ceramic could be used as an excellent material for fabrication of novel magnetic data storage devices.
Cellulose based polymers have shown tremendous potential as drug delivery carrier for oral drug delivery system (DDS). Hydroxyethyl cellulose (HEC) and hydroxypropyl cellulose (HPC) are widely explored as excipients to improve the solubility of poorly water soluble drugs and to improve self-life of dosage form. This work is an attempt to modulate the physicochemical properties of these cellulose derivatives using biofield treatment. The treated HEC and HPC polymer were characterized by X-ray diffraction (XRD), differential scanning calorimetry (DSC) and thermogravimetric analysis (TGA). The XRD studies revealed a semi-crystalline nature of both the polymers. Crystallite size was computed using Scherrer’s formula, and treated HEC polymer showed a significant increase in percentage crystallite size (835%) as compared to the control polymer. This higher increase in crystallite size might be associated with greater crystallite indices causing a reduction in amorphous regions in the polymer. However treated HPC polymer showed decrease in crystallite size by -64.05% as compared to control HPC. DSC analysis on HEC polymer revealed the presence of glass transition temperature in control and treated HEC polymer. We observed an increase in glass transition temperature in treated HEC, which might be associated with restricted segmental motion induced by biofield. Nonetheless, HPC has not showed any glass transition. And no change in melting temperature peak was observed in treated HPC (T2) however melting temperature was decreased in T1 as compared to control HPC. TGA analysis established the higher thermal stability of treated HEC and HPC. CHNSO results showed significant increase in percentage oxygen and hydrogen in HEC and HPC polymers as compared to control samples. This confirmed that biofield had induced changes in chemical nature and elemental composition of the treated polymers (HEC and HPC).
Authors: Mahendra Kumar Trivedi
Comments: 5 Pages.
Objective: Chloramphenicol and tetracycline are broad-spectrum antibiotics and widely used against variety of microbial infections. Nowadays, several microbes have acquired resistance to chloramphenicol and tetracycline. The present study was aimed to evaluate the impact of biofield treatment for spectroscopic characterization of chloramphenicol and tetracycline using FT-IR and UV-Vis spectroscopy. Methods: The study was performed in two groups (control and treatment) of each antibiotic. The control groups remained as untreated, and biofield treatment was given to treatment groups. Results: FT-IR spectrum of treated chloramphenicol exhibited the decrease in wavenumber of NO2 from 1521 cm-1 to 1512 cm-1 and increase in wavenumber of C=O from 1681 cm-1 to 1694 cm-1 in acylamino group. It may be due to increase of conjugation effect in NO2 group, and increased force constant of C=O bond. As a result, stability of both NO2 and C=O groups might be increased in treated sample as compared to control. FT-IR spectrum of treated tetracycline showed the downstream shifting of aromatic C-H stretching from 3085-3024 cm-1 to 3064-3003 cm-1 and C=C stretching from 1648-1582 cm-1 to 1622-1569 cm-1 and up shifting of C-N stretching from 965 cm-1 to 995 cm-1. It may be due to enhanced conjugation effect in tetracycline, and increased force constant of C-N (CH3 ) bond of tetracycline as compared to control. The results indicated the enhanced stability of treated tetracycline as compared to control. UV-Vis spectra of biofield treated chloramphenicol and tetracycline showed the similar lambda max (λmax) to their respective control. It revealed that the chromophore groups of both antibiotics remained same as control after the biofield treatment. Conclusion: Based on FT-IR spectroscopic data, it is speculated that due to increase in bond strength and conjugation effect after biofield treatment, the chemical stability of both the drugs might be increased as compared to control.
Authors: Elias Khalil
Comments: 9 Pages.
Washing is considered as the final process in denim jeans production and is the core of denim finishing. It is the key to create the style in denim garments which is now becoming an art of creating fashion trends. The three dimensional (3D) effect is one of the most demandable finishing techniques for producing vintage denim jeans. Various types of 3D making equipments and methods are applied to jeans after resin application for producing such 3D effects. Denim jeans are then dried and finally cured in an oven for specific time at right temperature for getting final product
In this review we wish to report a most probale approach of normalisation on partition function.
And also the nature of thermal wave function as a normalised parameter.
Authors: Bezverkhniy Volodymyr Dmytrovych
Comments: 34 Pages.
Using the concept of three-electron bond one can represent the actual electron structure of benzene, explain specificity of the aromatic bond and calculate the delocalization energy. It was shown, that functional relation
y = a + b/x + c/x^2 fully describes dependence of energy and multiplicity of chemical bond on bond distance.
In this article carbon-to-carbon bonds are reviewed. Using these dependences it is possible to calculate chemical bound energy by different bond distance or different multiplicity of chemical bond, that makes possible to calculate delocalization energy of benzene molecule.
Authors: Bezverkhniy Volodymyr Dmytrovych.
Comments: 8 Pages.
Analysis of images made in techniques of atomic force microscopy (AFM) of high resolution in pentacene and other aromatic systems shows that according to predictions, aromatic three-electron bond is deflected to the centre of aromatic nuclei, which clearly confirms the fact of existence of three-electron bond in benzene, pentacene and other aromatic systems. It also confirms the existence of this bond in carboxylate anions and other similar ions and molecules.
The existence of large aromatic monocycles has been proved impossible based on interaction
of three-electron bonds through the cycle at distances between the bonds (through the cycle) greater than 3.5 Å due to the lack of energy interaction (the length of chemical bonds is in the range of distances 0.74 Å – 3.5 Å).
The chemical bond (two-electron and three-electron) is considered on the assumption that the electrons in a chemical bond can be regarded as being in an entangled quantum state, that is, the chemical bond is seen as a
new "indivisible" particle. There has been provided an algorithm for calculating the two-electron chemical bond "on the tip of the pen". An attempt was made to explain the mechanism of interaction of particles in an entangled quantum state on the basis of a new model of the Interfering Universe.
Authors: Bezverkhniy Volodymyr Dmytrovych
Comments: 18 Pages.
Nothing prohibits to give a definition of the multiplicity of bond: the multiplicity of bond is the energy of bond expressed in dimensionless units. It is easy to show, that relation multiplicity = f(L) and Е = f(L), where multiplicity is multiplicity of bond, L – length of bond in Å, Е – energy of bond in kj/mole will be described by function y = a + b/x + c/x² for any types of bond (C-N, C-O, C-S, N-N, N-O, O-O, C-P).