Authors: George Rajna
Researchers in Dana-Farber's cBio Center have now demonstrated a powerful 'experimental evolution' method to discover details of protein shape and function, and the method may find uses across a very broad spectrum of biomedical research. [37] The discovery, published in Nature Communications, could help uncover treatments for age-related conditions, such as Alzheimer's disease, which are often caused by accumulation of misfolded proteins. [36] Korean researchers have used light to control the binding of two separate and inactive antibody fragments and generate a specific, timely immune response to antigens. [35] A new Empa study recently published in Nature Communications shows how this amazing behavior can be improved-and even used to treat injuries and tissue damage. [34] Scientists at Johns Hopkins Medicine report they have created a tiny, nanosize container that can slip inside cells and deliver protein-based medicines and gene therapies of any size-even hefty ones attached to the gene-editing tool called CRISPR. [33] Protocells-artificial cells-that are active and mimic living cells by moving independently and that are biocompatible and enzymatically active are now possible using an improved method developed by Penn State researchers. [32] Pioneering new research into the way in which cells communicate with each other could hold the key to unlocking new, improved treatment for life-threatening diseases, including cancer. [31] Researchers at the University of Illinois at Chicago have demonstrated that magnetic nanoparticles can be used to ferry chemotherapy drugs into the spinal cord to treat hard-to-reach spinal tumors in an animal model. [30] Small vessel vasculitis-inflammation of the small blood vessels-appears as a stain of tiny, red dots covering the skin that, depending on the severity, can evolve into painful pustules or ulcers. [29] Scientists from the University of Freiburg have developed materials systems that are composed of biological components and polymer materials and are capable of perceiving and processing information. [28] Nanotechnology may provide an effective treatment for Parkinson's disease, a team of researchers suggests. [27]
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