Statins and Death Due to Any Cause – All Doubts Removed?

Authors: Ilija Barukčić

Objective: To date, it is quite common to claim that some patient groups benefit from statin therapy in both primary and secondary prevention of cardiovascular disease while equally the use of higher-intensity statin therapies is emphasized. In this Review, the efficacy of statin therapy in light of the study data available is explored. Methods: All in all, 40 studies with a sample size of n = 88388 were re-analyzed. The exclusion relationship was used to test the null-hypothesis: a certain statin does exclude death due to any cause. The causal relationship k was used to test the data for causality. The level of significance was set to Alpha = 0,05. Results: The data of the studies reanalyzed provide convincing evidence that statins unfortunately do not exclude death due to any cause. An immediate statin therapy discontinuation should be considered. Conclusions: Overwhelming evidence suggests that the risk potential harmful effects of statin therapy far outweigh any real or perceived benefit. Keywords: Statins, death, causal relationship.

Comments: 29 Pages. (C) Ilija Barukčić, 2019, Jever, Germany. All rights reserved.

Download: PDF

Submission history

[v1] 2019-12-06 12:00:41

Unique-IP document downloads: 8 times is a pre-print repository rather than a journal. Articles hosted may not yet have been verified by peer-review and should be treated as preliminary. In particular, anything that appears to include financial or legal advice or proposed medical treatments should be treated with due caution. will not be responsible for any consequences of actions that result from any form of use of any documents on this website.

Add your own feedback and questions here:
You are equally welcome to be positive or negative about any paper but please be polite. If you are being critical you must mention at least one specific error, otherwise your comment will be deleted as unhelpful.

comments powered by Disqus