Metronidazole is an antibiotic useful for the treatment of vaginosis, trichomoniasis, giardiasis, etc., which are caused by the bacteria and parasites. The research work aimed to estimate the impact of the Trivedi Effect®-Consciousness Energy Healing Treatment on the physicochemical and thermal properties of metronidazoleusing modern analytical techniques. The test sample metronidazole was divided into control and treated sample. The control sample did not receive Biofield Energy Treatment; whereas the treated sample received the Biofield Treatment remotely by a renowned Biofield Energy Healer, Dahryn Trivedi. The particle size values were significantly increased by 14.37% (d10), 9.94% (d50), 7.9% (d90), and 9.41% [D(4,3)]; hence, the specific surface area was significantly decreased by 10.58% in the treated sample compared with the control sample. The PXRD peak intensities and crystallite sizes were significantly altered ranging from -97.25% to 401.64% and -63.08% to 344.35%, respectively, however, average crystallite size was significantly increased by 24.4% in the treated sample compared with the control sample. The latent heat of fusion and latent heat of decomposition were significantly increased by 7.64% and 12.13%, respectively in the treated sample compared to the control sample. The total weight loss was decreased by 1.34%; however, the residue amount was significantly increased by 76.46% in the treated sample compared with the control sample. The Biofield Energy Treatment might generate a new polymorphic form of metronidazole which would offer better powder flow ability and more thermos table compared with the control sample. The treated metronidazole would be very useful in designing better pharmaceutical formulations that might offer better therapeutic responses against the bacterial infections in the vagina, stomach, liver, skin, joints, brain, and respiratory tract, aspiration pneumonia, fungating wounds, rosacea, abdominal infections, periodontitis, amoebiasis, etc.
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[v1] 2019-08-02 02:43:00
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