Physics of Biology


Extracellular Disease Diagnosis

Authors: George Rajna

A research team led by the University of Notre Dame is working to cut the test time for disease biomarkers. The new timeline-30 minutes instead of 13 hours-uses even smaller sample sizes to offer a new liquid biopsy option. [32] A new focused ultrasound approach-low-energy, rapid, short-pulsed ultrasound-can open the blood-brain barrier (BBB) using microbubbles and deliver drugs more uniformly and more safely than methods based on long ultrasound pulses. [31] MIT engineers have designed tiny robots that can help drug-delivery nanoparticles push their way out of the bloodstream and into a tumor or another disease site. [30] Researchers have shown that existing optical fibre technology could be used to produce microscopic 3-D images of tissue inside the body, paving the way towards 3-D optical biopsies. [29] Researchers at MIT, working with surgeons and oncologists at Massachusetts General Hospital (MGH), have now developed a way to improve the accuracy of this surgery, called debulking. [28] Scientists at the University of Bristol have invented a new technology that could lead to the development of a new generation of smart surgical glues and dressings for chronic wounds. [27] Elaborate molecular networks inside living cells enable them to sense and process many signals from the environment to perform desired cellular functions. [26] RNA sequencing is a technique used to analyze entire genomes by looking at the expression of their genes. [25] Researchers from the University of Chicago have developed a high-throughput RNA sequencing strategy to study the activity of the gut microbiome. [24] Today a large international consortium of researchers published a complex but important study looking at how DNA works in animals. [23] Asymmetry plays a major role in biology at every scale: think of DNA spirals, the fact that the human heart is positioned on the left, our preference to use our left or right hand ... [22]

Comments: 58 Pages.

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[v1] 2019-05-21 05:14:45

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