Physics of Biology

   

Possible Traces of Resonant Signaling in the Genome

Authors: Ivan Savelyev, Max Myakishev-Rempel

Since so far, there is no published evidence for the resonant genomic signaling, we attempted searching for its traces in the genome computationally. Since we believe that the majority of repetitive sequences in the genome are involved in meaningful resonant signaling, we hypothesized that some of the unique (non-repetitive) sequences in the genome might have evolved to resonate with the genomic repeats. Accordingly, we hypothesized that it is not necessary for the unique sequence to be identical to the repeat, that for resonance, it might need to be only superficially similar to the sequence of the repeat: for example, it is possible that some oscillations involve primarily the electron clouds of the aromatic rings (Savelyev et al., 2019). This way only purine-pyrimidine structure of the resonating sequences should be similar and their primary sequences could be different. This simplification of the sequence from the primary sequence to the purine-pyrimidine sequence is further called "purine code". Similarly, for the oscillations which involve primarily the proton clouds of the delocalized protons of the hydrogen bonds in basepairs, only the patterns of these bonds should be similar and the primary sequence could be different. This simplification of the sequence from primary to strong/weak (3 bonds /2 bonds per base pair) is further called "strong code".

Comments: 26 Pages.

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[v1] 2019-05-09 21:52:58

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