Physics of Biology

   

Neutrons Paint Atomic Portrait

Authors: George Rajna

Direct observations of the structure and catalytic mechanism of a prototypical kinase enzyme—protein kinase A or PKA—will provide researchers and drug developers with significantly enhanced abilities to understand and treat fatal diseases and neurological disorders such as cancer, diabetes, and cystic fibrosis. [22] The ability to grow large protein crystals is the single biggest bottleneck that limits the use of neutron protein crystallography in structural biology. [21]

Comments: 37 Pages.

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Submission history

[v1] 2019-03-20 14:32:36

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