Physics of Biology

   

Protein Resistance Mechanism

Authors: George Rajna

In order to understand why bacteria are becoming immune to previously well-functioning drugs, scientists are penetrating ever deeper into the molecular structure of cells. [24] Proteins rarely work alone, they interact, form protein complexes or bind DNA and RNA to control what a cell does. [23] Using tiny micromotors to diagnose and treat disease in the human body could soon be a reality. [22] Scientists at the University of Illinois at Urbana-Champaign have produced the most precise picture to date of population dynamics in fluctuating feast-or-famine conditions. [21] For planetary protection, this indicates that more stringent cleaning steps may be needed for missions focused on life detection and highlights the potential need to use differing and rotating cleaning reagents that are compatible with the spacecraft to control the biological burden. [20] Now an international team of researchers has found a new way to investigate how Tb bacteria inactivate an important family of antibiotics: They watched the process in action for the first time using an X-ray free-electron laser, or XFEL. [19] A protein complex called facilitates chromatin transcription (FACT) plays a role in DNA packing within a nucleus, as well as in oncogenesis. [18] An LMU team now reveals the inner workings of a molecular motor made of proteins which packs and unpacks DNA. [17] Chemist Ivan Huc finds the inspiration for his work in the molecular principles that underlie biological systems. [16] What makes particles self-assemble into complex biological structures? [15] Scientists from Moscow State University (MSU) working with an international team of researchers have identified the structure of one of the key regions of telomerase—a so-called "cellular immortality" ribonucleoprotein. [14]

Comments: 40 Pages.

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[v1] 2018-10-27 05:03:39

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