Physics of Biology


Regulation of Oligopeptide Transporter Pept1 (Slc15a1) in Disease and Application in Clinical Nutrition

Authors: Ming-Yi Liu

Many studies have demonstrated the di- and tripeptides is a major mechanism by which the digestion products of proteins are absorbed. The oligopeptide transporter PepT1 is localized to the brush-border membrane and mediates the absorption in mammalian intestine. Recently, regulations of PepT1 activity by a variety of pathological conditions have been studied. Critical illness, malnutrition and metabolic disorder could induce the modulation of protein and gene expressions of PepT1. We reviewed and analyzed by searching PubMed, google scholar database and reference literature to provide a theoretical basis for clinical nutrition support.

Comments: 11 Pages.

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Submission history

[v1] 2018-06-23 11:14:53

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