Authors: Ilija Barukčić
Objective: Parvovirus B19 appears to be associated with several diseases, one among those appears to be systemic sclerosis. Still, there is no evidence of a causal link be-tween parvovirus B19 and systemic sclerosis. Methods: To explore the cause-effect relationship between Parvovirus B19 and sys-temic sclerosis, a systematic review and re-analysis of studies available and suitable was performed. The method of the conditio sine qua non relationship was used to proof the hypothesis without Parvovirus B19 infection no systemic sclerosis. The mathematical formula of the causal relationship k was used to proof the hypothesis, whether there is a cause effect relationship between Parvovirus B19 and systemic sclerosis. Significance was indicated by a p-value of less than 0.05 Result: The data analyzed support the Null-hypothesis that without Parvovirus B19 infection no systemic sclerosis. In the same respect, the studies analyzed provide evi-dence of a (highly) significant cause effect relationship between Parvovirus B19 and systemic sclerosis. Conclusion: This study supports the conclusion that Parvovirus B19 is the cause of systemic sclerosis. Keywords Parvovirus B19, systemic sclerosis, causal relationship
Comments: 28 Pages. pp. 28. Copyright © 2017 by Ilija Barukčić, Jever, Germany. Published by:
[v1] 2018-01-31 15:05:32
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