Authors: Ilija Barukčić
Objective: Accumulating evidence indicates that the gut microbiome has an increas-ingly important role in human disease and health. Fusobacterium nucleatum has been identified in several studies as the leading gut bacterium which is present in colorectal cancer (CRC). Still it is not clear if Fusobacterium plays a causal role. Methods: To explore the cause-effect relationship between Fusobacterium nucleatum and colorectal cancer, a systematic review and re-analysis of studies published was performed. The method of the conditio sine qua non relationship was used to proof the hypothesis without Fusobacterium nucleatum infection no colorectal cancer. The mathematical formula of the causal relationship k was used to proof the hypothesis, whether there is a cause effect relationship between Fusobacterium nucleatum and colorectal cancer. Significance was indicated by a p-value of less than 0.05 Result: The data analyzed support the Null-hypothesis that without Fusobacterium nucleatum infection no colorectal cancer. In the same respect, the studies analyzed provide highly significant cause effect relationship between Fusobacterium nucleatum and colorectal cancer. Conclusion: The findings of this study suggest that Fusobacterium (nucleatum) is the cause of colorectal cancer.
Comments: 37 pages. Copyright © 2018 by Ilija Barukčić, Horandstrasse, Jever, Germany. Published by:
[v1] 2018-01-14 16:15:21
Unique-IP document downloads: 26 times
Vixra.org is a pre-print repository rather than a journal. Articles hosted may not yet have been verified by peer-review and should be treated as preliminary. In particular, anything that appears to include financial or legal advice or proposed medical treatments should be treated with due caution. Vixra.org will not be responsible for any consequences of actions that result from any form of use of any documents on this website.
Add your own feedback and questions here:
You are equally welcome to be positive or negative about any paper but please be polite. If you are being critical you must mention at least one specific error, otherwise your comment will be deleted as unhelpful.