Authors: Robert S. Shaw
The idea that ion channel proteins physically rotate to enhance ion flow through the membrane is reviewed, in light of recent experimental results. Although there is still no definite answer to the question presented in the title, some recent work can be interpreted as supporting this notion. As a bonus, we present a general theory of anesthesia. Anesthetics, and alcohol, are dissolved in the membrane lipids, and (perhaps) do not directly bind to ion channels or pores. Instead, they change the properties of the surrounding lipids, thus compromising the rotations of the pores, and producing the anesthetic effects.
Comments: 14 Pages.
[v1] 2017-12-31 15:37:31
Unique-IP document downloads: 14 times
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