Physics of Biology

   

Biological Structure from Limited Data

Authors: George Rajna

Understanding the 3D molecular structure of important nanoobjects like proteins and viruses is crucial in biology and medicine. [25] A quantum sensor developed by a team headed by Professor Jörg Wrachtrup at the University of Stuttgart and researchers at the Max Planck Institute for Solid State Research in Stuttgart, now makes it possible to use nuclear magnetic resonance scanning to even investigate the structure of individual proteins atom by atom. [24] Scientists at the University of Nottingham are working with University College London (UCL) on a five year project which has the potential to revolutionise the world of human brain imaging. [23] Scientists in Greece have devised a new form of biometric identification that relies on humans' ability to see flashes of light containing just a handful of photons. [22] A research team led by Professor CheolGi Kim has developed a biosensor platform using magnetic patterns resembling a spider web with detection capability 20 times faster than existing biosensors. [21] Researchers at Columbia University have made a significant step toward breaking the so-called "color barrier" of light microscopy for biological systems, allowing for much more comprehensive, system-wide labeling and imaging of a greater number of biomolecules in living cells and tissues than is currently attainable. [20] Scientists around the Nobel laureate Stefan Hell at the Max Planck Institute for Biophysical Chemistry in Göttingen have now achieved what was for a long time considered impossible – they have developed a new fluorescence microscope, called MINFLUX, allowing, for the first time, to optically separate molecules, which are only nanometers (one millionth of a millimeter) apart from each other. [19] Dipole orientation provides new dimension in super-resolution microscopy [18] Fluorescence is an incredibly useful tool for experimental biology and it just got easier to tap into, thanks to the work of a group of University of Chicago researchers. [17] Molecules that change colour can be used to follow in real-time how bacteria form a protective biofilm around themselves. This new method, which has been developed in collaboration between researchers at Linköping University and Karolinska Institutet in Sweden, may in the future become significant both in medical care and the food industry, where bacterial biofilms are a problem. [16] Researchers led by Carnegie Mellon University physicist Markus Deserno and University of Konstanz (Germany) chemist Christine Peter have developed a computer simulation that crushes viral capsids. By allowing researchers to see how the tough shells break apart, the simulation provides a computational window for looking at how viruses and proteins assemble. [15] IBM scientists have developed a new lab-on-a-chip technology that can, for the first time, separate biological particles at the nanoscale and could enable physicians to detect diseases such as cancer before symptoms appear. [14] Scientists work toward storing digital information in DNA. [13] Leiden theoretical physicists have proven that DNA mechanics, in addition to genetic information in DNA, determines who we are. Helmut Schiessel and his group simulated many DNA sequences and found a correlation between mechanical cues and the way DNA is folded. They have published their results in PLoS One. [12] We model the electron clouds of nucleic acids in DNA as a chain of coupled quantum harmonic oscillators with dipole-dipole interaction between nearest neighbours resulting in a van der Waals type bonding. [11] Scientists have discovered a secret second code hiding within DNA which instructs cells on how genes are controlled. The amazing discovery is expected to open new doors to the diagnosis and treatment of diseases, according to a new study. [10] There is also connection between statistical physics and evolutionary biology, since the arrow of time is working in the biological evolution also. From the standpoint of physics, there is one essential difference between living things and inanimate clumps of carbon atoms: The former tend to be much better at capturing energy from their environment and dissipating that energy as heat. [8] This paper contains the review of quantum entanglement investigations in living systems, and in the quantum mechanically modeled photoactive prebiotic kernel systems. [7] The human body is a constant flux of thousands of chemical/biological interactions and processes connecting molecules, cells, organs, and fluids, throughout the brain, body, and nervous system. Up until recently it was thought that all these interactions operated in a linear sequence, passing on information much like a runner passing the baton to the next runner. However, the latest findings in quantum biology and biophysics have discovered that there is in fact a tremendous degree of coherence within all living systems. The accelerating electrons explain not only the Maxwell Equations and the Special Relativity, but the Heisenberg Uncertainty Relation, the Wave-Particle Duality and the electron’s spin also, building the Bridge between the Classical and Quantum Theories. The Planck Distribution Law of the electromagnetic oscillators explains the electron/proton mass rate and the Weak and Strong Interactions by the diffraction patterns. The Weak Interaction changes the diffraction patterns by moving the electric charge from one side to the other side of the diffraction pattern, which violates the CP and Time reversal symmetry. The diffraction patterns and the locality of the self-maintaining electromagnetic potential explains also the Quantum Entanglement, giving it as a natural part of the Relativistic Quantum Theory and making possible to understand the Quantum Biology.

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[v1] 2017-07-11 09:05:24

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