[Objective] Evaluate on the treatment efficacy and safety for transcranial magnetoelectric encephalopathy treatment instrument (brand name: AOBO Alzheimer’s Treatment Instrument) treatmenting mild to moderate alzheimer’s disease. [Methods] Methods 80 patients with mild to moderate AD [Hachinski ischemia score ≤ 4 cent, degree of dementia（CDR=1.0）or (CDR=2.0)]were double center，randomized，double blind，Parallel，placebo controlled, clinical trial for 8 weeks, including treatment group and control group, each of 40 case. All the patients were given regular basic medical treatment and standardized nursing care, The patients of treatment group were treated with Transcranial magnetoelectric encephalopathy treatment instrument, The patients of control group were simulated treated with Transcranial magnetoelectric encephalopathy treatment instrument. [Results] Clinical trial results show, after treated for 8 weeks, Compared with the control group, the treatment group’s score of MMSE、ADAS-Cog and ADL improved significantly (difference between groups is P<0.001、0.0001、0.05). When treated 4 weeks, the score of MMSE and ADAS has been improved.There was no adverse reaction in the two groups. [Conclusions] The test statistical results proved, Transcranial magnetoelectric encephalopathy treatment instrument has good therapeutic effect for treatment mild to moderate alzheimer’s disease. It can improve the mental state, cognitive behavior and self-care ability of daily life, and it is used safety.
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[v1] 2017-07-03 02:02:34
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