Authors: Ilija Barukčić
Background: Many studies documented an association between a Helicobacter pylori infection and the development of human gastric cancer. None of these studies were able to identify Helicobacter pylori as a cause or as the cause of human gastric cancer. The basic relation between gastric cancer and Helicobacter pylori still remains uncer-tain. Objectives: This systematic review and re-analysis of Naomi Uemura et al. available long-term, prospective study of 1526 Japanese patients is performed so that some new and meaningful inference can be drawn. Materials and Methods: Data obtained by Naomi Uemura et al. who conducted a long-term, prospective study of 1526 Japanese patients with a mean follow up about 7.8 years and endoscopy at enrolment and in the following between one and three years after enrolment were re-analysed. Statistical analysis used: The method of the conditio sine qua non relationship was used to proof the hypothesis without a helicobacter pylori infection no development of human gastric cancer. The mathematical formula of the causal relationship was used to proof the hypothesis, whether there is a cause effect relationship between a helicobacter pylori infection and human gastric cancer. Significance was indicated by a P value of less than 0.05. Results: Based on the data published by Uemura et al. we were able to make evidence that without a helicobacter pylori infection no development of human gastric cancer. In other words, a Helicobacter pylori infection is a conditio sine qua non of human gastric cancer. In the same respect, the data of Uemura et al. provide a significant evidence that a helicobacter pylori infection is the cause of human gastric cancer. Conclusions: Without a Helicobacter pylori infection no development of human gastric cancer. Hel-icobacter pylori is the cause (k=+0,07368483, p Value = 0.00399664) of human gastric cancer.
Comments: 9 Pages. Copyright © 2016 by Ilija Barukčić, Jever, Germany. Published by Journal of Biosciences and Medicines, Vol.5 No. 2, p. 1-9. https://doi.org/10.4236/jbm.2017.52001
[v1] 2017-01-02 10:00:30
Unique-IP document downloads: 34 times
Add your own feedback and questions here:
You are equally welcome to be positive or negative about any paper but please be polite. If you are being critical you must mention at least one specific error, otherwise your comment will be deleted as unhelpful.