Authors: Ilija Barukčić
Objective. Many studies presented some evidence that EBV might play a role in the pathogenesis of rheumatoid arthritis. Still, there are conflicting reports concerning the existence of EBV in the synovial tissue of patients suffering from rheumatoid arthritis. Material and methods. Takeda et al. designed a study to detected EBV DNA is synovial tissues obtained at synovectomy or arthroplasty from 32 patients with rheumatoid arthritis (RA) and 30 control patients (no rheumatoid arthritis). In this study, the data as published by Takeda et al. were re-analysed. Results. EBV infection of human synovial tissues is a condition per quam of rheumatoid arthritis. And much more than this. There is a highly significant causal relationship between an EBV infection of human synovial tissues and rheumatoid arthritis (k= +0,546993718, p-value = 0,00001655). Conclusion. These findings suggest that EBV infection of human synovial tissues is a main cause of rheumatoid arthritis.
Comments: 5 Pages. Copyright © 2016 by Ilija Barukčić, Jever. Published by: Romanian journal of rheumatology, 27 (4), (2018), 148-163. https://rjr.com.ro/
[v1] 2016-12-28 07:08:27
Unique-IP document downloads: 189 times
Vixra.org is a pre-print repository rather than a journal. Articles hosted may not yet have been verified by peer-review and should be treated as preliminary. In particular, anything that appears to include financial or legal advice or proposed medical treatments should be treated with due caution. Vixra.org will not be responsible for any consequences of actions that result from any form of use of any documents on this website.
Add your own feedback and questions here:
You are equally welcome to be positive or negative about any paper but please be polite. If you are being critical you must mention at least one specific error, otherwise your comment will be deleted as unhelpful.