Silver nanoparticles (Ag-NPs) are among the most medical applications nanomaterials mainly due to its antimicrobial effect, plasmon resonance and its capacity to impregnate polymeric materials. Recently Ag-NPs have been used in water treatment systems, central venous catheters, burn dressing, as well as in biosensors for detecting levels of p53 protein associated with cancer development. Moreover, the Ag-NPs have been studied for being potentially dangerous to humans and environment. Ag-NPs are transformed under the ecosystems conditions and may even increase their aggressiveness. The aim of this paper is to investigate the current state of knowledge about the bactericidal effect of Ag-NPs, the main synthesis methods, its application based on antibiotic capacity, Ag-NPs environmental transformations and their impact on the human.
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