Physics of Biology


Relation of Physiological Variables and Health

Authors: Feng Lin

Based on the non-equilibrium thermodynamics point of view that a biological system is sustained by a local potential provided by stable entropy production, we construct a mathematical model to describe the metabolism of human body system. According to the stable and periodic property of human body system, the embryonic form of the model is constructed by dimensional analysis. Based on the mathematical model, stability analysis is used to discuss the response to perturbation which corresponds to the influence on human health. With the help of physiology and medical science, the parameters in the model are determined by empirical formulas in physiology. The correspondence of parameters and the observable variables such as body temperature, body weight, heart rate etc is found out. As an example, an interesting result obtained from our model is that overweight adults, even though healthy in the medical examination reports, faces the risk of being sick, because overweight decreases the metabolic frequency, however, it drives the human body system "farther" from equilibrium (death). This result shows that the body weight of over weighted ones will gradually increase rather than staying at a stable interval. Our method provides a new approach of predicting human health according to the observable vital signs.

Comments: 16 Pages. mathematical and system science method is used to study biological system

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Submission history

[v1] 2016-03-10 08:24:51 (removed)
[v2] 2016-06-23 03:00:37

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