Authors: Mark R. Brenneman
This enzyme is an example of moonlighting protein which is validated and replaced by alternative reference genes that link (in their nuclear forms) on the multifunctional properties of the enzyme GAPDH known as a key enzyme in glycolysis that contributes to a number of diverse cellular functions unrelated to glycolysis depending upon its subcellular location. GAPDH is a key enzyme in glycolysis the most commonly used expression is as a housekeeping gene.
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