Quantitative Biology


A Proposed Artificial Neural Network Classifier to Identify Tumor Metastases Part I

Authors: M. Khoshnevisan, Sukanto Bhattacharya, Florentin Smarandache

In this paper we propose a classification scheme to isolate truly benign tumors from those that initially start off as benign but subsequently show metastases. A non-parametric artificial neural network methodology has been chosen because of the analytical difficulties associated with extraction of closed-form stochastic-likelihood parameters given the extremely complicated and possibly non-linear behavior of the state variables. This is intended as the first of a three-part research output. In this paper, we have proposed and justified the computational schema. In the second part we shall set up a working model of our schema and pilot-test it with clinical data while in the concluding part we shall give an in-depth analysis of the numerical output and model findings and compare it to existing methods of tumor growth modeling and malignancy prediction.

Comments: 14 pages

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Submission history

[v1] 6 Mar 2010

Unique-IP document downloads: 118 times

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